AHFS Drug Information
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چکیده
Uses ■ Psychotic Disorders Thioridazine is used for the symptomatic management of psychotic disorders. However, because thioridazine has the potential for substantial, and possibly life-threatening, proarrhythmic effects and can precipitate sudden death, use of the drug is reserved for patients with schizophrenia whose disease fails to respond adequately to appropriate courses with at least 2 different antipsychotic agents, either because of insufficient efficacy or the inability to achieve an effective dosage due to intolerable adverse effects. In addition, use of thioridazine in patients with refractory schizophrenia has not been evaluated in controlled clinical trials and efficacy of the drug in such patients is not known.
منابع مشابه
Ability of online drug databases to assist in clinical decision-making with infectious disease therapies
BACKGROUND Infectious disease (ID) is a dynamic field with new guidelines being adopted at a rapid rate. Clinical decision support tools (CDSTs) have proven beneficial in selecting treatment options to improve outcomes. However, there is a dearth of information on the abilities of CDSTs, such as drug information databases. This study evaluated online drug information databases when answering in...
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INTRODUCTION This study evaluated whether pharmacogenomic information contained in the Food and Drug Administration (FDA)-approved package inserts of sixty-five drugs was present in five drug information resources. METHODS The study searched for biomarkers from the FDA package inserts in 5 drug information sources: American Hospital Formulary Service Drug Information (AHFS), Facts & Compariso...
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Acute heart failure syndromes (AHFS) remain a major cause of morbidity and mortality, in part because the development of new therapies for these disorders has been marked by frequent failure and little success. The heterogeneity of current approaches to AHFS drug development, particularly with regard to end points, remains a major potential barrier to progress in the field. End points involving...
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BACKGROUND Clinicians commonly rely on tertiary drug information references to guide drug dosages for patients who are receiving continuous renal replacement therapy (CRRT). It is unknown whether the dosage recommendations in these frequently used references reflect the most current evidence. OBJECTIVE To determine the presence and accuracy of drug dosage recommendations for patients undergoi...
متن کاملReassessment of dobutamine, dopamine, and milrinone in the management of acute heart failure syndromes.
The appropriate role of intravenous inodilator therapy (inotropic agents with vasodilator properties) in the management of acute heart failure syndromes (AHFS) has long been a subject of controversy, mainly because of the lack of prospective, placebo-controlled trials and a lack of alternative therapies. The use of intravenous inodilator infusions, however, remains common, but highly variable. ...
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تاریخ انتشار 2010